Name: Nathan De Beule
Vrije Universiteit Brussel (VUB)
Faculty of Medicine and Farmacy
Department of Hematology and Immunology
Tel: 02/477 44 01
Fax: 02/477 44 05
Education: Master in Medical Sciences (2012, VUB)
Multiple Myeloma (MM) is a currently incurable rare malignant plasma cell disease, which invariably relapses despite therapy. The objective of our project (OVER-MYR) is to understand the causes of drug resistance and relapse, develop novel strategies to overcome these, provide proof of principal for phase I/II trial, and thus impact on MM-patients survival. Currently-used drugs target both MM cells (MMC) and cells of the bone marrow (BM) microenvironment or niche that are critical for supporting MMC survival, proliferation and growth.